| Highest net patient revenue | Highest operating expenses |
|---|---|
| New York Presbyterian Hospital, New York $5,951,047,108 |
New York Presbyterian Hospital, New York $5,889,911,000 |
| Cleveland Clinic Hospital, Cleveland $5,164,424,360 |
Cleveland Clinic Hospital, Cleveland, Ohio $5,775,457,364 |
| KFH - Fontana, Fontana, Calif. $4,404,479,570 |
NYU Langone Hospitals, New York $4,358,450,898 |
| Stanford Health Care, Stanford, Calif. $4,132,132,686 |
Vanderbilt University Medical Center, Nashville, Tenn. $4,032,836,216 |
| NYU Langone Hospitals, New York $4,101,296,000 |
Memorial Hospital for Cancer and Allied Diseases, New York $3,879,672,753 |
| AdventHealth Orlando, Orlando, Fla. $3,769,768,374 |
Massachusetts General Hospital, Boston, Mass. $3,820,595,000 |
| KFH - Los Angeles, Los Angeles, Calif. $3,653,264,695 |
Montefiore Medical Center, Bronx, N.Y. $3,810,931,000 |
| UCSF Medical Center, San Francisco, Calif. $3,620,962,130 |
Stanford Health Care, Stanford, Calif. $3,798,273,217 |
| UT MD Anderson Cancer Center, Houston, Texas $3,480,505,919 |
UCSF Medical Center, San Francisco, Calif. $3,575,085,309 |
| Vanderbilt University Medical Center, Nashville, Tenn. $3,442,776,569 |
Indiana University Health, Indianapolis, Ind. $3,469,131,965 |